Translational Technologies and ResourcesThe University of Florida has a wide range of resources potentially available to support Clinical and Translational Science. However, a need exists to further develop certain new technologies and resources, while others had been fragmented and not adequately visible or accessible to faculty researchers and trainees. The CTSI intends to transform the accessibility, quality and quantity of translational technologies and resources available to CTS investigators at UF by accomplishing the following goals.
- Establish the Translational Technologies and Resources (TTR) Program. The Program will consist of an integrated network of cores that will have their own organizational and governing structure and will provide advanced technologies to CTSI investigators.
- Provide and coordinate access to the cores through the CTSI’s Research Portal and CTSI Research Project Navigators.
- Launch the following new technology-based cores for CTS researchers and provide raining in cutting-edge translational technologies.
Since the advent of the CTSI, the following cores have been established:
- A new Genotyping Core has been derived as a synergy of two existing facilities at UF for targeted determination of genotypes on genomic DNA from biological samples.
- A Biomedical Mass Spectrometry Core specializes in the development of assays for the quantification of small molecules in complex media (plasma, serum, urine, tissues, cell cultures, etc) using mass spectrometry for both human and animal studies.
- A new Metabolomics Core formed involving existing state-of-the-art mass spectrometry and nuclear magnetic resonance (NMR) spectroscopy resources on campus to provide both targeted and global analysis of small molecules in biological materials. This new core also has benefited by the collaboration with Duke University’s Steadman Center for Nutrition and Metabolism.
- The new CTSI Biorepository has been formed through reorganization and expansion of what is now a diversified network of human DNA, serum and tissue repositories to provide new access by investigators to these valuable resources.
- The new CTSI Human Imaging Core has been formed to provide imaging services for human-subject research.
- A new Biobehavioral Core provides broad expertise at UF in the application of human-validated assessment measures of behavioral concomitants of disease or therapeutic interventions.