Join us to celebrate the research of MD-PhD students, and CTSI trainees, scholars and pilot awardees representing multiple departments and colleges across the University of Florida.
Dr. Nelson is a physician-scientist in the Department of Pediatrics at the UF College of Medicine. He holds an appointment in the Department of Environmental and Global Health at the UF College of Public Health and Health Professions. Dr. Nelson is the PI of a large NIH-funded laboratory at the UF Emerging Pathogens Institute and maintains field laboratories in Haiti and Bangladesh.
The Harrell Medical Education Building serves as a national model, providing a dynamic environment for training UF medical students and physician assistant students to practice safe, effective and compassionate clinical care.
Welcome and opening remarks
Duane Mitchell, MD, PhD, is the Phyllis Kottler Friedman Professor in the Department of Neurosurgery. UF Assistant Vice President for Research, Associate Dean for Clinical and Translational Sciences at the UF College of Medicine, and Director of the UF Clinical Translational Science Institute (CTSI).
Mark Segal, MD, PhD, Director, MD-PhD Training Program
Master of Ceremonies, Amy Peiper, MD-PhD Trainee
Eric Nelson, MD, PhD, FAAP
HMEB Learning Studio #135
Meeting ID: 913 8373 4749
Private lunch for students
MD-PhD & TL1 to interact with Dr. Nelson
Open poster session & reception
Interactive poster session
The MD-PhD Training Program is at the interface of discovery and development where we are transcending individual disciplines for the “team science” paradigm. Here, enthusiastic and interactive researchers, creative minds, and cutting-edge technology work together to apply and advance science. The goal of the MD-PhD Training Program is to enable scholars to obtain the best training in their intended research areas while working closely with an outstanding faculty.
The CTSI TL1 Training Program provides predoctoral trainees with the skills required to develop a career in multidisciplinary clinical and translational research. TL1 Teams are comprised of two or more PhD students from different degree programs in different colleges. Teams collaborate to develop new team-specific aims that expand the scope of their individual dissertation projects based on a common research interest, e.g., a human disease being investigated at different levels (molecular to population), with different experimental approaches or data analysis methods, and/or at different parts of the T0-T4 continuum.
The KL2 Program is a multidisciplinary program for junior faculty, that provides two years of financial support and research training to develop the skills necessary to build a well-funded, collaborative career in clinical/ translational research.
End of the symposium
Pediatric health equity is at the heart of Dr. Nelson’s research. He is trained clinically in pediatrics and scientifically in molecular microbial pathogenesis. His team’s strategy has been to use cholera as a model system to discover opportunities to improve clinical and scientific response to large-scale infectious disease outbreaks. The premise is that outbreaks prey most on marginalized populations, and improving outbreak response for these populations conveys equity.
Cholera has devastating impacts on poor and vulnerable populations worldwide and shares commonalities with other diarrheal diseases that collectively represent the second leading cause of death for children between the ages of 1 month and 5 years of age. Clinically, Dr. Nelson’s team asks how might emerging technology be leveraged to improve access to high-quality care, including increased antibiotic stewardship.
To do this they build clinical decision-support technologies to identify, map and better manage diarrheal disease outbreaks. As they evaluate these tools in clinical trials, the trials inform an ambitious basic science agenda to define how the selective pressures of antibiotics and lytic bacteriophage impact diarrheal disease severity, disrupt the commensal intestinal microflora, select for antibiotic and bacteriophage resistance, influence transmission and diagnostic performance. The integration of clinical trials and basic science has made for impactful translational research that benefits patients and improves a fundamental understanding of pathogenesis, disease transmission, antimicrobial resistance and diagnostic design requirements.
These clinical and scientific research lines have exposed a bias towards research at centralized clinics and hospitals. This negates the identification and study of health events in households that do not require seeking care. Therefore, Dr. Nelson has expanded the scope of his research to identify methods to improve access to care at the level of households by combining telemedicine and medication delivery, as well as investigating infection and transmission of infectious agents within household unit clusters.
Using these diverse skill sets, they joined in the fight against Covid-19 and launched parallel studies on COVID-19 infection and transmission among children and their household contacts inside and outside the USA. Now in the COVID-19 era, Dr. Nelson’s goal is to continue striving for healthcare equity for children globally while adapting to the new and different pressures imposed by the COVID-19 pandemic.
|presenter name||mentor||presentation title|
|Frederick Ashby, MPHP||Coy Heldermon, MD, PhD||Quantification of AAV Delivery Methods by Next Generation Sequencing|
|Miles Cameron||Andrew Judge PhD||Respiratory Muscle Pathology in Esophageal Adenocarcinoma Patients|
|Leanne Dumeny||Larisa Cavallari, PharmD||HR-Based Prediction Model in ARA-Prescribed Heart Failure Patients|
|Zachary Krumm||Todd Tolde, MD, PhD||Approaching A Mechanism Driving Stress-Induced Changes In Eating Behavior and Obesity|
|John Figg||Benjamin Canales. MD, MPH||Refractory Nephrolithiasis Ameliorated with Qsymia: A Case Report|
|Aditya Mahadevan, BS||Helen Jones, PhD||Transcriptional Associations Between Diabetes, Congenital Heart Defects, and the Human Placenta|
|Amy Peiper||Stephanie Karst, PhD||MNV-WU23 as a new tool for studying norovirus-induced gastrointestinal disease|
|Holly Ryan||Erika Moore,PhD|
|Daniel Stribling||Rolf Renne, PhD||Containerized CUT&RUN Analysis Allows Characterization of Histone H3.3 Deposition in Kaposi’s Sarcoma-Associated Herpesvirus (KSHV) Infection|
|Puchong Thirawatananond||Todd Brusko, PhD||The effect of CD226 co-stimulation on regulatory T cell development and function|
CTS TL1 presentations
|PRESENTER NAME||MENTOR||PRESENTATION TITLE|
|Karen Awura Adjoa Ronke Coker||Sarah McKune, MPH, PhD||A CTS Team Approach to Incorporating Black Women’s Conceptualization of Trust in the Development of a Mindfulness Practice Tool Tailored for the Reproductive Provider Space|
|Tyler Nesbit, MA, MS||Larry Forthun, PhD||A CTS Team Approach to Incorporating Black Women’s Conceptualization of Trust in the Development of a Mindfulness Practice Tool Tailored for the Reproductive Provider Space|
|Andrew Rainey, MPH||Mariola Edelmann, PhD||A CTS Team Approach to Wastewater-Based Epidemiology of Non-Typhoidal Salmonella in Gainesville, FL.|
|Lisa Emerson||Anthony Maurelli, PhD||A CTS Team Approach to Wastewater-Based Epidemiology of Non-Typhoidal Salmonella in Gainesville, FL.|
|Courtney Wilkinson||Lori Knckstedt, PhD||A CTS Team Approach to immune signatures of PTSD susceptibility|
|Phil Mackie||Habibeh Khoshbouei, PhD||A CTS Team Approach to immune signatures of PTSD susceptibility|
|Jennifer Applebaum||Barbara Zsembik, PhD||A CTS Team Approach to Assess the Impact of Pet Ownership on Allostatic Load Trajectories|
|Carlyn Ellison||Sherrilene Classen, PhD||A CTS Team Approach to Assess the Impact of Pet Ownership on Allostatic Load Trajectories|
|Hannah Anderson||Libin Rong, PhD||A CTS Team Approach to Modeling Migration and Suppression of CCR2+/CX3CR1+ Myeloid Cells in Glioblastoma|
|Greg Takacs||Jeffrey Harrison, PhD||A CTS Team Approach to Modeling Migration and Suppression of CCR2+/CX3CR1+ Myeloid Cells in Glioblastoma|
|Natalie Koskela-Staples||David Fedele, PhD||A TL1 Team Approach: Physician Strategies to Promote Physical Activity Among Youth with Comorbid Asthma and Overweight/Obesity|
|Jacqlyn Yourell||Jennifer Doty, PhD||A TL1 Team Approach: Physician Strategies to Promote Physical Activity Among Youth with Comorbid Asthma and Overweight/Obesity|
|Yara Skaf||Reinhard Laubenbacher, PhD||A TL1 Team Approach to Topological Data Analysis for Interpretation of Medical Images and Risk Stratification in COVID-19|
|Osama Dasa, MD, MPH||Thomas Pearson, MD, PhD, MPH||A TL1 Team Approach to Topological Data Analysis for Interpretation of Medical Images and Risk Stratification in COVID-19|
KL2 Presentations, Pilot Awards and TRACTS
|presenter name||UNIVERSITY||mentors||presentation title|
|Brittany Bruggeman, MD||UF, KL2||Michael Haller, MD; Martha Campbell-Thompson, PhD||A Serum Exocrine Enzyme as a Biomarker of Response to Immunotherapy in Type 1 Diabetes|
|Jennifer Schoch||UF, KL2||Leslie Parker, PhD and Josef Neu, MD||Skin Microbiome Sampling in the Neonate|
|Julia Sheffler, PhD||FSU,KL2||Sylvie Naar, PhD||Pilot Trial of a Motivational Interviewing and Cognitive Behavioral Therapy (MI-CBT) Ketogenic Nutrition Adherence Program for Older Adults|
|Jessica Bahorski, PhD, APRN||FSU-Pilot||Heather Flynn, PhD and Melissa Radey, PhD (both from FSU), Co-I is Dominick Lemas, PhD at UF||Identification of Research Priorities during the 4th Trimester in Maternal-Infant Dyads|
|Brandon Lucke-Wold, MD, PhD||TRACTS||Brian Hoh, MD, MBA||Neuroinflammation and Subarachnoid Hemorrhage: Novel Treatment Approach for Cerebral Vasospasm|