University of North Carolina at Chapel Hill

10-28 R25 Web Banner

Course Overview


This three-day power and sample size workshop will provide training for scientists in selecting a valid sample size for multilevel and longitudinal study designs. The workshop is accessible to all, from graduate students to senior researchers, and requires a basic statistical background. Instructors are Keith E. Muller, Ph.D., professor at the University of Florida College of Medicine, and Deborah H. Glueck, Ph.D., associate professor at the University of Colorado School of Public Health. Sponsors include the North Carolina Translational and Clinical Sciences (NC TraCS) Institute and the Gillings School of Global Public Health Department of Biostatistics at the University of North Carolina at Chapel Hill and the University of Florida’s Clinical and Translational Science Institute.


Date


Host Location Date Registration Deadline
University of North Carolina at Chapel Hill Michael Hooker Research Center, Rm. 0001 Tues., March 13, 2018 – Thurs., March 15, 2018 Tues., March 6, 2018

Cost


UNC Students & Affiliates Contact Melissa Hobgood at mhobgood@bios.unc.edu to begin registration:
Course Number: BIOS 690 (1 credit)
Section: 001
Non-UNC Affiliates $1,000

Registration


UNC Students & Affiliates Contact Melissa Hobgood at mhobgood@bios.unc.edu to begin registration:
Course Number: BIOS 690 (1 credit)
Section: 001
Non-UNC Chapel Hill Affiliates Click Here

For questions, please contact Sandra Salloum, academic specialist, at SandraSalloum@ufl.edu.

Workshop Objectives


At the end of the workshop, attendees will be able to:

  • Understand a framework and strategy for study planning
  • Write study aims as testable hypotheses
  • Describe a longitudinal and multilevel study design
  • Write a statistical analysis plan
  • Ensure sufficient sample size for racial or ethnic subgroups for studies of disparities
  • Demonstrate the feasibility of recruitment
  • Describe expected missing data and dropout
  • Write a power and sample size analysis that is aligned with the planned statistical analysis
  • Write the design, analysis, power and sample size sections for a grant
  • Use expert feedback to improve the product

Workshop Schedule


While the exact content of each workshop will vary, please see the model schedule below for an idea of what is covered each day.

Day 1: Study Design
  • 9 a.m.-12 p.m.: Understanding four common study designs and factors in experimental design
  • 12-1 p.m.: Instructional workshop on the ethics of power and sample size
  • 1-2 p.m.: Optional accessible walk and talk with faculty or break time
  • 2-5 p.m.: Understanding the hypothesis, linking study designs to statistical models and understanding types of study outcomes
Day 2: Power and Sample Size Analysis
  • 9 a.m.-12 p.m.: Choosing the appropriate statistical test, understanding correlation structure in multilevel and longitudinal studies, understanding power and Type I error and aligning power analysis and data analysis
  • 12-1 p.m.: Working lunch with faculty on class projects or optional break
  • 1-2 p.m.: Optional accessible walk and talk with faculty or break time
  • 2-5 p.m.: Summarizing a study design, predicting missing data and dropout and accounting for missing data and dropout
Day 3: Writing the Grant
  • 9 a.m.-12 p.m.: Collecting inputs for power analysis, studying power via statistical simulation, demonstrating recruitment feasibility and handling multiple study aims
  • 12- 1 p.m.: Working lunch with faculty on class projects or optional break
  • 1-2 p.m.: Optional accessible walk and talk with faculty or break time
  • 2-5 p.m.: Writing the sample size section for your grant, graphics for power and sample size, power for subgroup analysis and getting funded
Post-Class Assignments
  • Four homework assignments
  • One two-hour in-person or online lab to receive guidance on assignments 1-4
  • Final assignment
  • Consisting of a one-page statistical analysis plan and power or sample size analysis
  • Three hours of in-person or online lab to receive help on final assignment.
  • One-hour interactive video conference via GoToMeeting with students and workshop instructors

Additional Resources & Information


The Michael Hooker Research Center Blue Cross Blue Shield Auditorium (Rm. 0001) is in compliance with the the Americans with Disabilities Act.

Parking information: parking is available for $8/day in the Cardinal/Dogwood Lot

Accessibility Resources and Services

Mother’s Room: Rosenau Hall 227A