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TL1 Training Grant

Program Overview

TL1 Trainees at CTSI Research Day 2015

TL1 Trainees at CTSI Research Day 2015. Clockwise from bottom right: Dane Phelan, Cuc Tran, Aliyah Snyder, Shannon Roff and Jacquelyn Walejko.

  • Complete the CTS Interdisciplinary Concentration
  • Identify Basic & Clinician Scientist Co-Mentors
  • At least one CTS Specific Aim required for dissertation project
  • TL1 Teams and TL1 Mentoring Teams
  • Submission of CTS review paper relevant to team research topic
  • Present research at annual national Translational Science conference (ACTS) during 2 years of funding
  • Present research at annual CTSI Annual Research Symposium
  • Semi-annual progress reports

The CTSI TL1 Predoctoral Training Program provides junior trainees with the skills required to develop a career in multidisciplinary clinical and translational research. The program uses a team-science approach and provides mentoring and didactic training for predoctoral students performing clinical and/or translational research in health-related fields at UF.

TL1 trainees will initially receive one year of funding, including a stipend (current year level: $23,376*), tuition waiver, and GatorGradCare health insurance via a Graduate Research Assistantship; $2,500 for lab and training-related expenses; and a $1,500 travel allowance to attend and present research at the annual Translational Science conference. A second year of funding may be awarded based on performance, progress and available funding.

Contact the program with any questions at training@ctsi.ufl.edu.

*If a TL1 trainee’s current stipend is above $23,376, a mentor should supplement the stipend from non-federal funds to the original stipend level.

The UF Clinical & Translational Science Institute is not currently accepting applications for the TL1 Predoctoral Training Grant.  The next application cycle will open in January 2017, with an application deadline in March.  Predoctoral students entering their second or third year of graduate study in 2017-18 and who have not completed their dissertation proposal defense will be eligible to apply.  The CTSI welcomes applicants from any of its partner graduate programs across 11 UF colleges.  See the web page links below for more information.  The TL1 program emphasizes collaboration and team science, and TL1 trainees will be expected to form TL1 Teams of two or more students from different graduate programs to collaborate on some aspect of their dissertation research.  Information sessions about the TL1 program will be arranged during the Fall semester.

Eligibility Requirements

  1. Applicants must be U.S. citizens or permanent residents per NIH policy and entering their second or third year of doctoral graduate study. Students from populations underrepresented in the biomedical, clinical, behavioral and social sciences are encouraged to apply (more information).
  2. Doctoral students from the following partner graduate programs spanning 11 colleges are eligible to apply.  Additional partner programs can be added, so applications from students in other relevant graduate programs may be considered.
    • Agricultural & Life Sciences: Nutritional Sciences
    • Dentistry: DMD-PhD Program
    • Engineering: Biomedical Engineering, Materials Science & Engineering, Electrical Engineering
    • Health & Human Performance: Applied Physiology & Kinesiology, Health Education & Behavior
    • Journalism & Communications: Mass Communication
    • Liberal Arts & Sciences: Chemistry
    • Medicine: Interdisciplinary Program in Biomedical Sciences (Biochemistry & Molecular Biology, Cancer Biology, Genetics, Immunology & Microbiology, Molecular Cell Biology, Neuroscience, Physiology & Pharmacology), MD-PhD Program, Health Outcomes & Policy
    • Nursing: Nursing Science
    • Pharmacy: Medicinal Chemistry, Pharmaceutics, Pharmacodynamics, Pharmaceutical Outcomes and Policy, Clinical Pharmaceutical Sciences
    • Public Health & Health Professions: Clinical and Health Psychology, Communication Science & Disorders, Public Health, Rehabilitation Sciences
    • Veterinary Medicine: Veterinary Medical Sciences (Physiological Science, Infectious Diseases & pathology, Large Animal Clinical Science, Small Animal Clinical Science)
    • Multi-College Programs: Biostatistics, Epidemiology, Genetics & Genomics
  3. Applicants must apply in the first or second year of Ph.D. studies, prior to completing doctoral candidacy exams.
  4. Applicants should have strong academic credentials and good communication skills.
  5. Applicants must be able to commit to all course and research training requirements of the training program.
  6. Applicants must propose a research project relevant to human health, which should include at least one component of clinical and/or translational research as defined by the NIH.
  7. Applicants should demonstrate interest in developing a career in multidisciplinary, translational biomedical research.
  8. Applicants must identify two faculty mentors (one basic science and one clinical/translational) and demonstrate strong mentor support.

Program Requirements

TL1 Trainees must:

  • Complete the Clinical & Translational Science Interdisciplinary Concentration;
  • Present their research at the annual Translational Science (Association for Clinical & Translational Science) conference during each year of TL1 funding, and at the annual CTSI Research Day each year until graduation.
  • Identify Basic & Clinician Scientist Co-Mentors
  • Design at least one CTS Specific Aim for dissertation project
  • Participate in a TL1 Team
  • Submit for publication in a peer-reviewed journal a CTS review paper relevant to team research topic
  • Submit semi-annual progress reports

TL1 Teams

TL1 Trainees will be expected to identify at least one other TL1 Trainee as a research collaborator.  For this funding cycle, students may apply as preformed TL1 Teams, or teams may be formed after the final selection of TL1 Trainees.  Preference may be given to applicants who have applied as a team.  Need help finding potential team members?  We can provide a list of other prospective applicants.  Please e-mail Susan Gardner (sgard@ufl.edu) your name, e-mail address, graduate program, brief research description, brief description of your research expertise, and a brief description of what you’re looking for in a collaborator.

Application Process

Applicants must assemble an application packet that includes a completed TL1 application form (see link below) and supporting materials, which include applicant statements; a research plan for the proposed research project, which must have both clinical/ translational and basic science components; and supporting materials from two proposed mentors (one basic science mentor and one clinical & translational science mentor).  Finalists will be interviewed by the TL1 Advisory Committee.

New applications must be submitted electronically by 5:00 p.m. on Friday, March 25, 2016.  Paper documents will not be accepted.  Interviews of finalists will take place on Monday & Tuesday, April 18-19, and awards are expected to be announced no later than April 29, 2016.   TL1 Application Spring 2016

Definitions

  1. Clinical Research: Patient-oriented research, including epidemiologic and behavioral studies, outcomes research, and health services research. Patient-oriented research is research conducted with human subjects (or on material of human origin such as tissues, specimens, and cognitive phenomena) in which a researcher directly interacts with human subjects. It includes research on mechanisms of human disease, therapeutic interventions, clinical trials, and development of new technologies, but does not include in vitro studies using human tissues not linked to a living individual. Studies falling under 45 CFR 46.101(b) (4) are not considered clinical research for purposes of this definition. (Source: http://grants.nih.gov/grants/glossary.htm)
  2. Translational Research: Translational research includes two areas of translation. One is the process of applying discoveries generated during research in the laboratory, and in preclinical studies, to the development of trials and studies in humans. The second area of translation concerns research aimed at enhancing the adoption of best practices in the community. Cost-effectiveness of prevention and treatment strategies is also an important part of translational science. (Source: http://grants.nih.gov/grants/glossary.htm)
  3. Permanent Resident: someone who has been granted authorization to live and work in the United States on a permanent basis. As proof of that status, a person is granted a permanent resident card, commonly called a “green card.” (Source: US Citizen and Immigration Services)